US policy toward the Indo-Pacific region has undergone a long formation process due to the impact of strategic, security and economic factors. During the Cold War, the US strategy mainly focused on Europe and East Asia to deal with the Soviet Union and the Socialist Bloc. However, since the end of the Cold War, changes in the global geopolitical structure have highlighted the importance of the Indo-Pacific region. This region has an important strategic geopolitical position with sea routes connecting Europe, the Middle East and East Asia, along with the strong increase of China’s influence. In addition, fluctuations in regional security such as disputes in the East Sea, the East China Sea, the rise of India and changes in the security structure in the Southeast Asian region have prompted the US to adjust its strategic policy. From the Rebalance (Pivot) strategy to Asia - Pacific under President Barack Obama to the "Free and Open Indo-Pacific" strategy under President Donald Trump and Joe Bidenshows that the US is focusing on maintaining an order based on international law, building new alliances and strengthening its role in the region to deal with challenges from rivals, protecting US interests in a region that is becoming the focus of global power competition.