This study examines groundwater quality concerns in Mandsaur city, Madhya Pradesh, with particular attention to nitrate and pesticide contamination. The agricultural intensity of the region, especially its prominence in opium cultivation, has contributed significantly to groundwater degradation through fertilizer leaching and pesticide runoff. Our research explores an innovative remediation approach combining silver nanoparticles and activated charcoal in a dual-filtration system. The silver nanoparticles target nitrate contamination through catalytic reduction processes, while activated charcoal effectively removes pesticide residues through adsorption mechanisms. Field testing across multiple sites in Mandsaur revealed substantial improvements in water quality parameters following treatment. This approach addresses contamination issues specific to Mandsaur's groundwater profile and agricultural patterns, offering a practical solution tailored to local conditions. The findings have important implications for public health in this mid-sized city where groundwater serves as the primary drinking water source. Implementation of this treatment technology could significantly benefit Mandsaur's residents while providing a model for similar agricultural regions facing comparable water quality challenges.