Knowledge of the risks associated with misuse of acetaminophen among self-medication users visiting pharmacies during the covid-19 pandemic in Abidjan

Due to the SARS-CoV-2 Covid-19 pandemic, acetaminophen has been widely recommended by health authorities and has led the majority of patients seeking treatment in private pharmacies. However, if misused, severe hepatotoxicity with a very poor prognosis may occur. The aim of our study was to assess the level of knowledge about the risks associated with acetaminophen misuse among peoples visiting pharmacies in Abidjan to purchase acetaminophen without a prescription during the COVID-19 pandemic. A multicentre cross-sectional survey was conducted from February 2021 to September 2021 among patients visiting 10 private pharmacies in Abidjan to purchase a paracetamol-containing medicine without a prescription. A questionnaire was administered by a student using the Kobocollect application. An overall score for knowledge of the proper use of acetaminophen was determined (score > 6 points/9) and specific knowledge of the risks associated with misuse was assessed. A total of 300 participants with mean age of 35.3 years 15.8 years old participated in the survey, of whom only 16% had sufficient knowledge about acetaminophen and its proper use. Only 26% of respondents were aware of the risk of hepatotoxicity in the event of an overdose, and 34% believed that there was no risk when consuming alcohol simultaneously with acetaminophen. Our findings during the COVID-19 pandemic demonstrate the need to adjust health policies and improve communication with the public in order to prevent the risk of unintentional acetaminophen poisoning.