English translation of Gao-De Li’s 1986 Chinese-language article titled as ‘abnormalities in chromatin fibre configuration and malignant Tumour formation’

Forty years ago, when I was 30-years old, I published a Chinese-language article named as ‘Abnormalities in chromatin fibre configuration and malignant tumour formation’. By literature search, this article might be the first one over the world, which proposed that 3D genome structure might be closely linked to gene expression, cell differentiation, and tumour formation. The assumption of ‘cancer reversal’, and ‘reversal drugs’ were also proposed in this article. To help researchers understand this article, I have used Google Translate to translate the original article into English, with a few minor changes. Besides, since this article might occupy a very important position in exploring history of 3D genome structure development, it is a must to translate this Chinese article into English.